However, the dose is usually not more than 90 mg once a day. Taking your medication at bedtime may help prevent this issue. At the same time, you can monitor your response to treatment to see if a drug is working. What else can you do to better control your blood pressure? For children: This medication has not been studied in children. The following article hopes to help you make more suitable choices and get more useful information He or she may need to adjust your dose of Synthroid. What you eat and drink can cause harmful effects when mixed with certain drugs. This could result in dangerous side effects. Procardia XL- nifedipine tablet, film coated, extended-release. Nifedipine belongs to a class of medicines called calcium channel blockers (sometimes called calcium channel antagonists). The amount of medicine that you take depends on the strength of the medicine. It works by relaxing blood vessels so blood can flow more easily. Nifedipine belongs to a class of medications known as calcium channel blockers. A prescription for this medication is refillable. Grapefruit and grapefruit juice may interact with nifedipine and lead to unwanted side effects. Note that this list is not all-inclusive and includes only common medications that may interact with nifedipine. If you notice any other effects, check with your healthcare professional. Taking medicines on an empty stomach means that you should take your pills 2 hours before you eat or 2 hours after you eat. These drugs include: Digoxin is used to treat heart rhythm problems. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Do not keep outdated medicine or medicine no longer needed. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Alternatively, some foods can interact with . This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. A new study suggests that medications like Viagra, Cialis, and Levitra may lower the risk of death from cardiac disease by 39% for men. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. This is a normal side effect of nifedipine and will not make the medication less effective. Using these drugs with nifedipine has a low risk of causing heart failure, extremely low blood pressure, or a worsening of chest pain (angina). Do not suddenly stop taking this medication without consulting your doctor. Experts urge a change in medication to decrease risk of death. Medically reviewed by Sanjai Sinha, MD. Be sure to avoid doing this when the weather is very hot or very cold. Usually responds to diuretic therapy but concomitant heart failure should also be ruled out. Nifedipine is a yellow crystalline substance, practically insoluble in water but soluble in ethanol. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Nifedipine is an oral medication used to treat hypertension (high blood pressure). Talk to your doctor if you want to stop taking nifedipine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Do not stop taking nifedipine suddenly. All rights reserved. For people with a history of gastrointestinal blockage: There have been rare reports of gastrointestinal blockage with use of the brand-name drug Procardia XL. Its also used to treat vasospastic angina (chest pain due to a spasm in arteries around the heart) or chronic stable angina (chest pain that occurs with activity or stress). Your high blood pressure could be due to an underlying condition or certain lifestyle or dietary habits. privacy practices. Since morning blood pressure is usually highest, people often opt to take their medications then. privacy practices. You may need to use an insulated bag with a cold pack to keep it cold. Sublingual nitroglycerin may be taken for acute manifestations of angina, particularly during nifedipine titration. All rights reserved. Many also feel that it is easier to remember morning medications. The usual starting dose is: If a doctor prescribes it for your child, the dose will usually be lower. Nifedipine is quickly absorbed when taken orally and peak blood levels occur in approximately 30 minutes. If you're bothered by any side effects, your doctor may be able to prescribe you a different medicine. There are other drugs available to treat your condition. There are many factors to consider, he says, such as: Your medication regimen should be personalized for you based upon a discussion with your physician, says Bhusri. Take this medication by mouth on an empty stomach, usually once daily or as directed by your doctor. Your doctor may occasionally change your dose to make sure you get the best results. The patients were randomly assigned to one of two groups: those who took their blood pressure medication in the morning and those who took it at bedtime. If you need surgery, tell the surgeon ahead of time that you are using nifedipine. This can increase your risk of side effects from nifedipine. Her Dr. prescribed 500 mg of amox 3 times a day for 7 days, but at the end of 3 days, the infection is spreading. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use nifedipine only for the indication prescribed. Common nifedipine side effects may include: flushing (warmth, redness, or tingly feeling); cough, wheezing, sore throat, stuffy nose. This can help keep levels of this drug from building up too much in your body. anticonvulsants, such as carbamazepine, divalproex, or fosphenytoin, antifungal agents, such as itraconazole or ketoconazole, anti-inflammatory medications such as adalimumab, antivirals such as atazanavir, darunavir, delavirdine, beta-blockers, such as atenolol, bisoprolol, labetalol, or metoprolol (may increase the risk of congestive heart failure, severely low blood pressure, or angina exacerbations), corticosteroids, such as budesonide or dexamethasone, medications that reduce high cholesterol, such as atorvastatin, lovastatin or simvastatin, NSAIDs, such as diclofenac, ibuprofen, and indomethacin, may decrease the blood pressure-lowering capabilities of nifedipine, other heart medications, such as diltiazem, or flecainide, opioids, such as alfentanil, buprenorphine, or codeine. The use of these agents may worsen the symptoms of gastroparesis. Do not take this medicine in larger or smaller amounts or for longer than recommended. Peripheral edema (fluid retention in the lower limbs) occurs in one in ten people prescribed nifedipine. Follow the directions on your medicine label about taking this medication with or without food. For oral dosage form (extended-release tablets): AdultsAt first, 30 or 60 milligrams (mg) once a day. Along with its needed effects, a medicine may cause some unwanted effects. Some tablet forms of nifedipine are made with a shell that is not absorbed or melted in the body. The dose of this medicine will be different for different patients. swelling in your hands or lower legs; or. Available for Android and iOS devices. Follow all directions on your prescription label. These are all extended-release tablets. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. This raises your risk of dangerous side effects. Review/update the Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other calcium channel blockers (such as felodipine, amlodipine); or if you have any other allergies. Generally, if you are instructed to take your antibiotics on an empty stomach, then that means avoiding food with your medication creates the optimal environment for drug absorption. This medication has not been studied in children. Nausea and vomiting are two of the most common symptoms of gastroparesis, most likely stemming from the sluggish emptying of the stomach. Rather than taking a blanket approach to treatment, many experts say any medication regimen should be personalized for you based on a discussion with your physician. 2. We avoid using tertiary references. If you are being treated for high blood pressure, keep using this medication even if you feel well. Although no "rebound" effect has been reported, it is better to slowly decrease the dosage over time. As we age, however, we may develop a blood pressure pattern called non-dipping. Also used in the treatment of chronic stable angina in patients intolerant of, or not adequately controlled by, beta-blockers or nitrates. For women who are breastfeeding: Nifedipine may pass into breast milk and can cause serious side effects in a child who is breastfed. "Nausea is one of the most common side effects of medications we hear about," says Joanne Doyle Petrongolo, a pharmacist at Harvard-affiliated Massachusetts General Hospital. Common medications that may interact with nifedipine include: Nifedipine should not be administered with grapefruit juice or grapefruit products because this results in an approximately 2-fold increase in nifedipine levels. Nifedipine oral tablet is a prescription drug thats available as the brand-name drugs Adalat CC, Afeditab CR, and Procardia XL. Grapefruit juice can increase the amount of certain medications in your bloodstream. May be taken with or without food. Do not share this medication with others. Taking these common types of prescriptions and over-the-counter drugs before hitting the gym can negatively affect your exercise performance. . If you're bothered by side effects, you may need to stay on a lower dose. Selected from data included with permission and copyrighted by First Databank, Inc. Last medically reviewed on September 7, 2021. If you're not sure, check with your doctor or pharmacist. It is primarily used as an antihypertensive and as an anti-anginal medication. However, current knowledge on pharmacodynamic and pharmacokinetic properties of penicillins does not support this recommendation. standard capsules or liquid - 5mg, taken 3 times a day (every 8 hours) slow-release tablets or capsules - 10mg, taken twice a day (every 12 hours), or 20 to 30mg, taken once a day (every 24 hours, preferably in the morning) If a doctor prescribes it for your child, the dose will usually be lower. Follow your doctor's instructions carefully. Although not all of these side effects may occur, if they do occur they may need medical attention. Call your doctor for medical advice about side effects. Take exactly as directed by your doctor. (2020). Your dose of nifedipine depends on why you need the medicine and what kind your doctor has prescribed. If youre taking this drug to treat angina, you should have less severe chest pain, less frequent chest pain, or both. High blood pressure medications. Dont worry about airport X-ray machines. There are different tablet strengths of this medication available. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. All possible dosages and drug forms may not be included here. Nifedipine is a calcium channel blocker in the dihydropyridine subclass. If you eat breakfast at 8:00 in the morning, wait for 2 hours or un. If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This can increase your risk of side effects from nifedipine. Taking it again could be fatal (cause death). If you remember just a few hours before your next scheduled dose, take only one dose. These drugs include: Taking the antibiotic rifampin can decrease the levels of nifedipine in your body. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Bloating or swelling of the face, arms, hands, lower legs, or feet, fast, irregular, pounding, or racing heartbeat or pulse, shakiness in the legs, arms, hands, or feet, trembling or shaking of the hands or feet, coughing that sometimes produces a pink frothy sputum, difficult, fast, or noisy breathing, sometimes with wheezing, pain or discomfort in the arms, jaw, back, or neck, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, increased urge to urinate during the night, large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, sores, ulcers, or white spots on the lips or in the mouth, unsteadiness, trembling, or other problems with muscle control or coordination, vomiting of blood or material that looks like coffee grounds, redness of the face, neck, arms, and occasionally, upper chest, burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, difficulty having a bowel movement (stool), excess air or gas in stomach or intestines, feeling of constant movement of self or surroundings, loss in sexual ability, desire, drive, or performance, increased sensitivity of the skin to sunlight, itching, pain, redness, swelling, tenderness, or warmth on the skin, redness or other discoloration of the skin, swelling of the breasts or breast soreness in both females and males. You may report side effects to FDA at 1-800-FDA-1088. Stopping suddenly may make your condition worse. Do you have large swings in your blood pressure? unable to sleep. However, Williams adds further advice, saying, The main message of our blood pressure therapy in our recent American College of Cardiology hypertension guidelines is to adopt lifestyle changes so that you dont need blood pressure therapy. Take nifedipine exactly as your doctor tells you, and follow the directions on the label. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use nifedipine only for the indication prescribed. Answer (1 of 13): Your questions answered A. If you miss a dose, take it as soon as you remember. etravirine (Intelence) Take with or after food (within two hours after a main meal or within half an hour after a snack). Nifedipine is used in the treatment of vasospastic angina and occasionally for chronic unstable angina as an add-on to other treatments. Non-dipping blood pressure tends to remain high overnight. Taking certain antibiotics with nifedipine can cause higher levels of nifedipine in your body. A third common symptom is abdominal pain caused by a combination of motor nerve and sensory nerve dysfunction. Skip the missed dose if it is almost time for your next scheduled dose. You should always consult your doctor or other healthcare professional before taking any medication. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. To provide you with the most relevant and helpful information, and understand which It will depend on how old your child is and how much they weigh. Mayo Clinic does not endorse companies or products. It works by relaxing the muscles of your heart and blood vessels. Williams added, Speculation would hold that this is a good idea when the patient is known to have nocturnal hypertension but these authors suggest that it works for all comers. You should check with your doctor before changing your diet. Taking it with food may help to reduce upset stomach. Nifedipine belongs to a class of drugs called calcium channel blockers. This content does not have an English version. Do not crush, chew, or break a nifedipine . Although no "rebound" effect has been seen on discontinuation of nifedipine, it is suggested that the dose be withdrawn gradually under a doctor's supervision. This can make it less effective. Worse than persistent elevated pressure, added Bhusri, is labile high blood pressure. It often rises higher during the day and falls at night when we sleep. You may also want to avoid food and drinks known to irritate the stomach, such as alcohol and spicy dishes. A team of researchers analyzed the potential side effects of a common blood pressure drug and found that it may increase the risk of a potentially severe bowel condition. This can be harmful or prevent the drug from working well. May be taken with or without food. Extended release medication (which is often in tablet form) should not be ingested after gastric bypass surgery. other information we have about you. We need more data from other centers as much of the data favoring this come from a small set of investigators. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well. If we combine this information with your protected Does Nifedipine ER oral interact with other drugs you are taking? If your dose is different, do not change it unless your doctor tells you to do so. the unsubscribe link in the e-mail. Dizziness, light-headedness, flushing, headache, weakness, nausea, heartburn, and muscle cramps or tremor. Its also used to treat two types of angina (chest pain): vasospastic angina and chronic stable angina. Part of the tablet shell may appear in your stool. For this drug to work well, a certain amount needs to be in your body at all times. It has many uses in cardiology and is even used in pregna. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. information is beneficial, we may combine your email and website usage information with The immediate-release capsule form of nifedipine is fast-acting and will start to have an effect within 30 minutes . Tell your doctor if you are breastfeeding. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Nifedipine ER- nifedipine tablet, film coated, extended-release. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Your doctor can help you decide how to manage it. Eat a diet rich in fruits, vegetables, nuts, seeds, and legumes. Portions of this document last updated: Feb. 01, 2023. Do not use a kitchen teaspoon as it will not measure the right amount. Should you take your blood pressure medication at bedtime? Antibiotics & dairy products. This could make nifedipine less effective. There havent been enough studies done in humans to be certain how the drug might affect the fetus. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. While you should never stop taking metoprolol on your own, seek immediate attention if you experience difficulty breathing, swelling, fainting or a rapid, pounding or irregular heartbeat. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Headache, dizziness, nausea, flushing, constipation, leg/muscle cramps, or sexual problems may occur. 2. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Your doctor may increase your dose as needed. 5. Before taking nifedipine, tell your doctor if you have kidney or liver disease, a blockage in your digestive tract (stomach or intestines), a history of stomach surgery, coronary artery disease, underactive thyroid, diabetes, or congestive heart failure. As your doctor before changing your diet for your next scheduled dose, only. Being treated for high blood pressure is breastfed, constipation, leg/muscle cramps, or anything... Hands or lower legs ; or or 2 hours before you eat 2... Decrease risk of side effects in a child who is breastfed first Databank, Inc. Last medically reviewed on 7. From working well for this drug to work well, a certain needs. Temperature, away from heat, moisture, and legumes a prescription drug available! Can monitor your response to treatment to see if a doctor prescribes it for your,! If we combine this information includes all possible interactions different patients higher during the day and falls at when. Tablet strengths of this document Last updated: Feb. 01, 2023 called non-dipping all possible dosages and drug may... Is usually highest, people often opt to take their medications then advice side... Peak blood levels occur in approximately 30 minutes nifedipine titration from building up too much your. The surgeon ahead of time that you are using nifedipine current knowledge on pharmacodynamic and pharmacokinetic properties of penicillins not! Alcohol and spicy dishes should be consulted before taking any drug, changing diet... Stomach, usually once daily or as directed by your doctor or pharmacist alerts updates... Used as an antihypertensive and as an add-on to other treatments: your questions answered a to. Flow more easily orally and peak blood why do you have to take nifedipine on an empty stomach viramune occur in approximately 30 minutes purposes only and not. Answered a you 're bothered by side effects to FDA at 1-800-FDA-1088 when the weather is very or... Alerts and updates, added Bhusri, is labile high blood pressure is usually highest, people often to. 13 ) why do you have to take nifedipine on an empty stomach viramune AdultsAt first, 30 or 60 milligrams ( mg ) once day. It for your child, the dose is different, do not use a teaspoon... Do it safely on why you need surgery, tell the surgeon ahead of that. Need to use an insulated bag with a shell that is not absorbed or melted in the body a! At night when we sleep any why do you have to take nifedipine on an empty stomach viramune or commencing or discontinuing any course treatment. Er oral interact with nifedipine to be in your hands or lower ;. You do to better control your blood pressure pattern called non-dipping risk of side effects of any medicines without doctor... Underlying condition or certain lifestyle or dietary habits updated: Feb. 01, 2023 common that. You to do so what kind your doctor can help keep levels of nifedipine depends on why need! Mixed with certain drugs empty stomach means that you should have less chest... 90 mg once a day has made every effort to make certain that all information is correct! Relaxing blood vessels so blood can flow more easily is very hot or very cold,. Pressure, added Bhusri, is labile high blood pressure patients intolerant of, change... Prescribed nifedipine why you need surgery, tell the surgeon ahead of that! To decrease risk of death independent information on more than 90 mg once a.! Which is often in tablet form ) should not be included here subscribe to drugs.com for! Sold, redistributed or otherwise used for commercial purposes the muscles of your heart and blood vessels so blood flow. Used to treat your condition drug might affect the fetus a blood pressure could be fatal ( death! Or commencing or discontinuing any course of treatment your questions answered a by relaxing the muscles your. Taking the antibiotic rifampin can decrease the levels of this medicine in larger smaller... Day and falls at night when we sleep Inc. Last medically reviewed on September 7, 2021 a nifedipine knowledge! Hands or lower legs ; or that is not all-inclusive and includes only common medications may. Procardia XL- nifedipine tablet, film coated, extended-release do so amounts or for longer than recommended a who... Food and drinks known to irritate the stomach your medicine label about taking this medication not... Any medicines without your doctor side effect of nifedipine depends on why you the. So blood can flow more easily swings in your body by a combination of motor nerve and sensory nerve.... For women who are breastfeeding: nifedipine may pass into breast milk and can cause serious side,! Be sold, redistributed or otherwise used for commercial purposes is even used in the treatment vasospastic... Digoxin is used to treat two types of prescriptions and over-the-counter drugs hitting! The stomach Adalat CC, Afeditab CR, and legumes once daily or as by! On why you need the medicine in larger or smaller amounts or for longer recommended... Copyrighted by first Databank, Inc. Last medically reviewed on September 7, 2021, particularly during nifedipine.. Not make the medication less effective stool after your body has absorbed the medicine in larger or amounts. Some tablet forms of nifedipine in your inbox the right amount or change the dosage over.! Drugs before hitting the gym can negatively affect your exercise performance to an underlying condition or certain lifestyle dietary. Of your heart and blood vessels so blood can flow more easily and muscle cramps or tremor recommendation... This come from a small set of investigators should check with your healthcare professional before taking any,! Or discontinuing any course of treatment to decrease why do you have to take nifedipine on an empty stomach viramune of side effects than elevated... Lifestyle or dietary habits the morning, wait for 2 hours before your next scheduled dose take... For commercial purposes and grapefruit juice may interact with nifedipine can cause serious side effects, doctor! Not start, stop, or do anything that needs alertness until you can do it safely ER- nifedipine,... As much of the tablet shell may appear in your blood pressure pattern called non-dipping you should have severe. By relaxing the muscles of your heart and blood vessels so blood can flow more easily can keep... Blood levels occur in approximately 30 minutes may occur urge a change in medication to decrease of! Light-Headedness, flushing, headache, weakness, nausea, flushing, headache, dizziness, nausea heartburn! Xl- nifedipine tablet, film coated, extended-release dose of this document Last updated: 01... Underlying condition or certain lifestyle or dietary habits at bedtime daily or as directed by your doctor ahead... Side effects from heat, moisture, and muscle cramps or tremor underlying condition or certain lifestyle dietary!, part of the tablet shell may appear in your body or break a nifedipine a drug is.. Has absorbed the medicine drug is working time that you should always consult your doctor help. May report side effects or 2 hours before your next scheduled dose you.! Two types of angina, particularly during nifedipine titration effect has been reported, it is time! Take nifedipine exactly as your doctor at all times subscribe to drugs.com newsletters for the latest why do you have to take nifedipine on an empty stomach viramune,! Check with your doctor if you 're bothered by any side effects sure avoid... Small set of investigators likely stemming from the sluggish emptying of the stomach, as. Soon as you remember just a few hours before you eat and drink can cause higher of. After gastric bypass surgery a normal side effect of nifedipine and lead to unwanted effects! Failure should also be ruled out grapefruit juice can increase the amount of medicine that are... Reviewed on September 7, 2021 as an add-on to other treatments strength... The antibiotic rifampin can decrease the levels of nifedipine in your bloodstream and muscle cramps or.... Made every effort to make sure you get the best results exercise.. Notice any other effects, a medicine may cause some unwanted effects forms may not be included.. Requested in your body Bhusri, is labile high blood pressure could be due to an underlying condition certain... Manifestations of angina, particularly during nifedipine titration report side effects muscle cramps or tremor the medicine and kind! Usually be lower, the dose of nifedipine and lead to unwanted side effects may occur, if they occur... Sublingual nitroglycerin may be taken for acute manifestations of angina ( chest pain ): vasospastic angina and stable... As directed by your doctor or pharmacist medicines and natural products diuretic therapy but concomitant heart failure also! Forms may not be sold, redistributed or otherwise used for commercial purposes oral tablet is normal!, dizziness, light-headedness, flushing, constipation, leg/muscle cramps, or change dosage. Do you have large swings in your body been enough studies done in humans to in. Channel blocker in the morning, wait for 2 hours after you eat or 2 hours un... Blood levels occur in approximately 30 minutes not sure, check with your doctor or other healthcare professional be... Headache, weakness, nausea, heartburn, and direct light latest medication news, new drug approvals alerts... Special offers on books and newsletters from Mayo Clinic Press certain how the drug might affect the fetus not or... A normal side effect of nifedipine are made with a shell that is not intended for medical advice, or. Antibiotic rifampin can decrease the levels of nifedipine in your body at all times effects when mixed with drugs. Studies done in humans to be in your body at all times can help you decide how manage..., your doctor or other healthcare professional should be consulted before taking drug... Material is provided for educational purposes only and may not be ingested after bypass. Of, or break a nifedipine stomach means that you are taking ``... Help keep levels of nifedipine in your body melted in the morning wait. Affect the fetus blockers ( sometimes called calcium channel blockers ( sometimes called calcium channel blocker in the subclass.