I am 48 and not yet menopaused. What all this means is that infection with Clostridia is not at all uncommon and in people who are infected with Clostridia, consuming citrate turns up the activity of this pathogenic bacteria, which produces and releases some really toxic stuff that can cause all the symptoms you mention. K2 is required to activate the proteins that regulate where calcium is deposited in your body: Osteocalcin, which delivers calcium to bone where you want it, and Matrix Gla protein, which prevents calcium from depositing in soft tissues including your coronary arteries where you dont. But, after reading all the current research (more than 70 papers) on strontium, I started taking it again at a half dose to ensure my bones remain healthy. So, amount of calcium provided by AlgaeCal Plus is 720 mg/day, plus you need to look at your diet to see how much calcium you are typically getting from the foods you eat. If there is a line not to cross and the studies prove that ones strontium levels continuously increase when supplementing, how do you determine when to stop strontium intake? Hi Lara: In both the review articles I have written on a variety of topics on Longevity Medicine Review and as I was writing Your Bones, I have had quite a few questions for which I could not find answers in the published research, so I wrote the people whose published work indicated they were the seminal researchers involved. John. PSif you are eating gluten-containing grains, I urge you to consider eliminating them (wheat, barley, rye). Lumbar BMD, adjusted for bone strontium content, increased in a dose-dependent manner in the intention-to-treat population: mean annual slope increased from 1.4% with 0.5 g/d SR to 3.0% with 2 g/d SR, which was significantly higher than placebo (P < 0.01). The plaque build up in your carotid arteries definitely suggests you need more K2! And your BMD score will also be impacted if the technician running your scan does not place your body exactly as it was placed on your prior scan. In addition, rather than take the full 4 tablets of algae cal, I am increasing my calcium consumption from food and plan on reducing the algae cal to 3 tablets daily. Hope you will let me know how your DXA turns out. Any ideas as to why I could be high here? . re-absorb calcium passing through the kidneys in the bloodstream instead of losing it in urine The meals you have together with other amino acids will interfere with the uptake of amino acids. It is so helpful to have technical matters explained with such authority in understandable terms. Once improvement has been made then dropping down to a lower dose, say half to one-quarter this amount, may be sufficient. After reading your blog Im so excited to be trying something natural to increase my bone density and have purchased the Garden of Life Vitamin Code Grow Bone. Many thanks Lara and any suggestions would be appreciated. PMID: 27684387. Or is there some issue with her ability to absorb calcium as well? Also, breakfast time seems to be the meal which is most easily controlled for Calcium intake and, therefore Strontium is taken at this time. I have severe osteoporosis at age 56. Here are a few quotes (italics added by me) from this paper, again stressing that strontium deposits primarily in trabecular bone: Thus, I am unable to read the paper in which 170 mg of strontium is said to be more effective, so I do not know what was done and cannot give you more helpful feedback on this. Re lactoferrin, it looks quite promising. When I stop taking it the headaches stop. My favorite is plain, organic, whole milk Greek yogurt we have a dish full every night along with some berries or other fruit and a handful of nuts or gluten-free granola for dessert. Yes, your DXA BMD score will be impacted by strontium. If taking iron (or other vitamins) on an empty stomach causes stomach irritation, try eating a very light snack. They ALL returned to the exercise program and completed a modified regimen without problems. But again, this is a trade-off that has to be weighed based on how acute your infection is and how quickly you need that doxycycline to get into your body. Hi Lara, Looking forward to your response. I highly recommend it for you as well. That supplement is broken up into AM and PM formulations. Many thanks! Osteoporos Int. Re being insurance poor I am hoping that Dr. Grout will still be able to be helpful. In sum, the issue is NOT healthy bones as indicated by BMD, but exposure to pro-inflammatory, potentially carcinogenic forms of estrogen. thank you Hi, I have been taking calcium, calcium rich foods and exercising to keep my bones strong, but my bone density test still show low bone density in my right hip. "No." "But he's innocent!" A shrug. Meunier, P. J., Slosman, D. O., Delmas, P. D., Sebert, J. L., Brandi, M. L., That goes for both the density and the tensile quality of your bones. This enables more of the live bacteria to survive the acidity in your stomach and make their way to your intestinal tract. Stay well, Lara. Yes, all dairy is full cream, yogurt and NZ Cheddar cheese; unfortunately milk is homo/pasteurised and fresh is unobtainable. Aside from it, I was diagnosed with a bit high cholesterol level and a bit high of creatinine and on medication for this in one month. Long-term treatment with strontium ranelate increases vertebral bone mass without deleterious effect in mice. Strontium can be taken with or without food. Im also taking an EPA supplement that has 1536 mg. Im also thankful I can and I love salmon! In most people, strontiums effects on glutamate secretion promote relaxation and deeper, more restful sleep, but in some people, these effects cause next day grogginess or nap attacks. You could try taking your Strontium mid-day to see if this helps. The perfect time for NAC consumption is about thirty minutes . The reason for this is that MK-4 is very quickly metabolized, so it is gone within 6-8 hours. In this thread, you said, the amount of strontium provided in the full dose is not 682 mg. Strontium Boost is strontium citrate, which is 31% elemental strontium and 69% citrate. Ive been taking AlgaeCal for a few years but stopped the Strontium last November because my husband thought it might be causing the all-over body aches I was having. I live alone and lost my family. 2001 Sep;69(3):121-9. She lectures at medical conferences around the world and is a contributing author to the Textbook of Functional Medicine, the Textbook of Natural Medicine (Osteoporosis chapter, 5th edition, published 2020), and Integrative Therapies for Depression; co-author of The Encyclopedia of Healing Foods, and lead author of Natural Medicine Instructions for Patients; Your Bones: How You Can Prevent Osteoporosis & Have Strong Bones for Life, Naturally, and her latest book, Healthy Bones, Healthy You! Further increases occurred within an interval of 90-180 days, with the most recent, after 800 days, at the finger and ankle being 7 and 15 times higher than the initial baseline reading. Dpd testing is less used nowadays. Still, the optimal situation would have been to direct the women to take their strontium at a time of day several hours before or after consuming calcium-rich foods since this would have improved strontiums absorption. Obviously, strontium-89 is not strontium citrate, but Ive provided a couple of the references on this below if youre interested. I have also discussed many things that contribute to bone loss that you may not be aware of, and which you can avoid once you know about them. What are her vitamin D levels her (25(OH)D blood levels? Hi Marilyn, wowthanks so much for taking the time to send me such a complete picture of whats going on with you! My bloodwork is also great! just let me know. It did though. Cortical bone also accumulates far more slowly. I appreciate that you take the time to respond to not only my questions, but also to the questions of others who follow your blog. https://www.sciencedaily.com/releases/2008/07/080728081346.htm (actual paper: https://acsjournals.onlinelibrary.wiley.com/doi/full/10.1002/cncr.23674) The GAIL score discussed in this paper relates to indicators of a womans lifetime risk for invasive breast cancer. Osteoporosis does run in my family with both my grandmother and my mom struggling with this. Im asking because the mineral strontium does not cause these effects, but the citrate provided by Strontium Boost, which is strontium citrate, can if some unfriendly bacteria are present in your digestive tract. Strontium is a . I am surprised that Meuiner didnt get back to mehis actual email address is different than the one given in the articles, in fact the one given doesnt even work, luckily I found his actual contact info. Thanks for the compliment, very glad my article set your mind at ease regarding the use of strontium citrate to safely help you rebuild healthy bones. Likewise, the most common over-the-counter supplements are chemically bound to different molecules, such as citrate, lactate, carbonate, and gluconate. Once you are tested and find out where your imbalances are (and this will be clearly shown on the 24 Hour Urine test for all the estrogens, progesterone, DHEA, testosterone, your adrenal hormones and more), you can restore balance. many thanks, Sara. In addition, the expressions of metabolizing enzymes (CYP3A4/CYP3A9 and UDPG) showed 12 to 193-fold difference between human and rat intestine with distinct regional dependent expression patterns. We can help guide each other towards what is highly likely to be beneficial we cannot be each other. Improved healing response in delayed unions of the tibia with low-intensity pulsed ultrasound: results of a randomized sham-controlled trial. Hope this helps and that you will sail through menopause and emerge even stronger and healthier also you may notice that your itis conditions significantly improve or even vanish with the help of AlgaeCal Plus and Triple Power. Strontium ranelate improves bone resistance by increasing bone mass and improving architecture in intact female rats. I know it works, Lara, Lara: I have a green smoothie at least 5 days a week with collards or kale. https://www.mayoclinic.org/diseases-conditions/thumb-arthritis/symptoms-causes/syc-20378339 Unfortunately, as we age, cumulative damage to our joints over the years, particularly when low levels of chronic inflammation are present (which also promote bone loss), starts to show up. ? Hi Kay, Or, not? I do get MK-7 in the Algae-Cal, should I supplement 50mg more. Youll know what will work best for you just find a time of day when you can take your strontium several hours (3 4 hours would be ideal) apart from consuming calcium. It effectively prevents and repairs osteoporosis without the side effects of bisphosphonates. And a large 2 year trial has just concluded using MK-7 to arrest the progression of coronary artery disease. But like I said if you think you are reacting to something stop using it. Here are a number of reasons: AlgaeCal is a tropical species / Aquamin is a North Atlantic species What about the AlgaeCal Plus? In this study, 176 women over 40 years of age followed one of three different bone-health programs: Plan 1 used a bone-health supplement with vitamin D3 (800 IU), AlgaeCals plant-sourced form of calcium (720 mg), and vitamin K as MK-4 (1.5 mg) for one year. Can I take AlgaeCal & Strontium Boost ? AlgaeCal is untreated as it is clean and pure / Aquamin is bleached with Hydrogen Peroxide Thanks, I found the reference to this study in Lis thesis unfortunately, Li does not provide us with a footnote on it, just one for the 2004 paper by Meunier et al. The only form of strontium for which ADRs have ever been reported is the unnatural, drug form, strontium ranelate, which has never been approved for use in the U.S. and whose use is now severely restricted in Europe. I thought this might be in one of the two papers you kindly provided links to, but I could not find anything re thyroid in these, and I have seen nothing suggesting this in any of the papers on natural forms of strontium that I have read. Are you aware of the research on glutathione (given via nebulizer) for COPD it is VERY helpful! From AlgaeCal site: Myth #3 Strontium Skews DEXA Results too much to be reliable: So I need all the help I can get now God Bless you .Audra, Sorry, I forgot to say anything about genistein I would recommend eating more soyfoods (organic definitely, you do NOT want GMO soyor GMO anything else, for that matter). Many many thanks for your help once again. I quit all meds. DEXA rescheduled, machine was out of action this morning. We recommend trying to increase the magnesium in your diet as a first approach and have a handy list here that can help. Sorry, I should have explained that venous thrombosis is medical-speak for a blood clot (thrombus) that forms within a vein. I feel more prepared to defend my decision to take strontium boostI was concerned reading about potential heart risks and hearing doctors didnt recommend Strontium (including my friends doctor) but it seems this is misinformation and related to strontium ranelate. It would also be a very good idea to increase your intake of probiotics (beneficial digestive tract bacteria). So you take half the dosage of strontium (1 capsule) Do you still take the full dosage of algae cal plus (4 capsules)? SO MUCH to be grateful for this year, as always, Lara. Who can I ask about the optimal frequency of DEXA tests so I am properly monitoring my bone density? Environ Res. Of course, the elemental vs. compound difference can explain the seeming dosage discrepancy. Dont know where you live in Canada, but if anywhere near Vancouver, BC, I will be giving 5 Wellness Series lectures for Factors Group discussing bone health in Vancouver Oct 22-24. While a bone density scan will typically measure critical fracture sites such as the spine and hip, you can be assured that benefits are being seen elsewhere in the skeletal system. You are so lucky to live there! Magnesium (as Phosphate) 21mg For most people, 3 hours or even 2 hours will be sufficient. In the research, approximately 50% of the increase seen in BMD over 3 years of treatment with strontium was due to strontiums larger size, AND 50% of the increase seen in BMD was accurate. Is this a test that those of us who take strontium citrate should be taking? To me it seems to show, over a 5 year period, bone on strontium aging and becoming more infused with calcium and phosphorous and less with strontium. . Women using HRT were shown to have higher BMD and also greater risk of breast cancer. Not happy about this and I see on another forum that other people have this problem, also. The study to which you sent me a link is the only human study I could find, but recent papers indicate lactoferrin may be quite helpful. I have some older bottles(2 years) of strontium citrate3 caps = 750mgs. These claims subsided after Bolland MJ, Grey A. I am wondering if we whould be taking less stontium. What you really want is about another 100 mcg of MK-7 so you could take 2 capsules of the Low Dose K2 formula or 1 capsule of the Advanced Super K. Id check costs and go with whichever one is least expensive. Your email address will not be published. As you can see from the references listed below, in the Niu et al. I was wondering what your thoughts are regarding taking strontium citrate along with Boron to help build stronger bones? I decided to ask you about low dose strontium to see if you had read something I hadnt or would come to the same conclusion I was beginning to. Please let me know what you suggest in order to take the AlgaeCal Plus to ingest a healthy amount of calcium. I discuss the research on K2 and the 2 forms available as supplements in Your Bones. So, how can we put the data into USEFUL perspective? I want to share my new way to eat natto as it is not an easy food for westerners to eat! 2017 Feb;105(2):433-442. doi: 10.1002/jbm.a.35917. In regards to your question about strontium being taken as a single dose in the COMB study, this is not unusual. Hi Dianne, thanks for sharing and reaching out! If you have any other questions or need clarification, please feel free to email[emailprotected] or call our Bone Health Consultants at 1-800-820-0184! I bought your book and I use it as a reference It has been so informative. Why is it so much more effective? One ounce of chia seeds about 3 tablespoons will give you 176.68 milligrams of calcium. Perhaps the information in Lis thesis article was cited inaccurately? But let me reiterate, I am NOT paid to be a sales person for AlgaeCal. The most recent study showed higher levels of DHEA were associated with 0.49% less bone loss at the neck of the femur (Ghebre MA, Hart DJ, Hakim AJ, et al. Seemingly in Europe every time they move wheat from country to country they spray it with insecticide and of course you can imagine what that does to your system. Hi Patricia, Nonethelss, I believe this may indicate suboptimal vitamin K2 status, plus many studies have now demonstrated that vitamin K (and specifically K2) is needed for healthy bones and to prevent calcification of arteries and other soft tissues. https://www.facebook.com/lara.pizzorno.5/videos/10220954773329527/ I hope to be taking 340 mg/d of Strontium Boost for the next ~50 years. J Clin Endocrinol Metab. In our clinical research, strontium citrate showed no negative side effects, including no evidence was found in cardiovascular risk. States the following: You do not have to be suffering from 1/2 hourly hot flushes! I am doing many of the things you mentioned and have one more quick question. In Laura Pizzornos blog , she refers to the excretion of ranelic acid , and questions the non excreted portion. Please feel free to contact our Bone Health Consultants 7 days a week at 1-800-820-0184 (USA & Canada, toll-free) or email [emailprotected] for more information and personalized support! Moise H, Adachi JD, Chettle DR, Pejovi-Mili A. In recent years, HER2 has become an important biomarker and target of therapy for approximately 30% of breast cancer patients. AlgaeCal is USDA Certified Organic / Aquamin is not organic This is why you want to be sure to be consuming twice as much calcium (from diet and supplements combined) as strontium. When I first started taking AlgaeCal, I didnt realize this for several months. Obviously, what you are currently doing is not meeting YOUR needs. Put another way, using our 3rd study data in which the women saw an average annual increase of 1.04% (so 3.12% over 3 years). If you have a copy of Your Bones, please check the section on calcium where I have provided a table showing the best food sources of calcium (p. 207 in the book) along with how much calcium is present in a typical serving of each food. Strontium citrate is 31% elemental strontium and 69% citrate. Marilyn, Sorry, used to the post preview at NOH, lots of booboos! It would be nice to just swallow one pill that would help bones and all else! I take a PPI for stomach issues. As a result, a treatment with Strontium should not induce any alteration of bone mineral.. I hope this helps set your mind at ease and that you will be delighted with you upcoming DXA/TBS results. One other bit of information about calcium this mineral plays MANY essential-to-life roles in our bodies besides its use in our bones and teeth. The study found that the amount of bone loss directly correlated to the bacterial load found in the bones. My only consideration would be the quality control level of the company selling the product. of Missouri-Kansas City; Director of Residency Research in Pathology, Truman Medical Center.. (also, my blood pressure was rising significantly enough that my Dr put me on blood pressure meds), Hi Pam, I also e-mailed Meunier and asked if his cited study (or any he knew of) suggested 170 mg to be more effective than 680 mgas the above people are citing him as demonstrating that. I can only have a bone density test done every two to three years. After reading the abstract, I did not pull the full article.). YOU are the reason I wrote the book. postmenopausal vertebral osteoporosisa 2-year randomized placebo controlled His phone number is 480-767-7119. Dont hesitate to write if I can be of further help, Lara, Dear Dr. Pizzorno, I woke up today to find your email response to my question, and was pleasantly surprised that my email actually got a response and that too so personal and informative and such a good medical advise and details. In sum, calcium has plenty to do for us in addition to its use in maintaining healthy bones and teeth. The test is pricey and will not be covered by your insurance, so I would suggest you look into simply taking additional MK-7 I use Life Extensions Super K with Advanced K2 Complex and take 1 capsule AM and 1 capsule PM. If you have read my posts on strontium or listened to the #AskLaras in which I discuss strontium, you know that strontium greatly improves our ability to maintain healthy bones through MANY mechanisms not by replacing calcium in our bones so, even though your bones are now in good shape, to keep them healthy, continuing to take some strontium is a good idea. It really helped put my mind at ease. Meunier PJ, Slosman DO, Delmas PD, Sebert JL, Brandi ML, Albanese C, Lorenc R, Pors-Nielsen S, De Vernejoul MC, Roces A, Reginster JY. [Epub ahead of print]PMID: 22448872 And ever since being off it, I dont feel it hardly anymore It's a radioactive beta emitter, produced by nuclear fission with a half-life of 29 years. I was diagnosed with osteoporosis in July of 2009. If as much as 11.2% of the gain in BMD is an overestimation, you multiply 1.04 x .88 to see how much is an actual increase in this case, its 0.91%. Ive now heard from a number of women who find it simplest to take their strontium supplement right before going to bed so around 4 hours after their evening meal. Strontium ranelate: dose-dependent effects in established GENTLE + EASY TO DIGEST: Natures Nectar's Bone Builder is made with essential vitamins and minerals that are easy-to-digest and gentle on the body, even when taken on an empty stomach. Futhermore if bones follow the pattern of teeth ,then according to the study, An association between strontium in drinking water supplies and low caries prevalence in man, maybe I should take 5-10 mg/day . I looked again at his thesis, but could find no contact information there. This one really shouldn't . The label online didnt say how often to take it. They base their claims on these 2 studies: But in both cases the authors of the studies drew POSITIVE conclusions about strontiums bone supporting role, yet the uncredentialed author of the website drew negative conclusions! We do not eat meat, but if you do, be sure you choose meat from pasture-fed animals, not feedlot beef or cows that are given corn (which is typically GMO as well!) Gan To Kagaku Ryoho. Safety does come first for me, and if at 41 mg/day they saw changes in thyroid I would like to take less. For example, if you gained a modest 1% after taking strontium and you reduce that score by 10%, you STILL GAINED .9% of new bone. My neurologist couldnt find a cause but I havent started back up yet. Hi sml, I REALLY want this to work so any insight you have would be gratefully received. Since everyones physiology is unique, its safest to start out with 25 mg and gradually increase up to 50 mg over a couple of months. What a great insight of yours! Read more about Removing These Toxins Can Improve Your Bone Health, According to Dr. Trubow. I suggest the following: Print your own How to Take Your AlgaeCal Supplements PDF. If you have chronic kidney disease, you should not risk taking strontium. Please call our friendly Bone Health Consultants at 1-800-820-0184 (USA & Canada, 7 days a week) or email us at [emailprotected] for further support. Just be sure to have wild caught rather than farm-raised salmon. The end result of all this is that wheat has become much more harmful for us. Also, if your digestion is impaired or you are taking an acid-lowering drug, you will not be properly breaking down the proteins in your food, and undigested protein fragments that gain entry into your bloodstream can provoke many kinds of adverse reactions, including the skin symptoms you are experiencing. Heres a quote from a paper discussing the differences among readings from different DXA machines: The theoretical values of the strontium ratio were 11.0 for the Hologic Discovery, 9.9 for the GE-Lunar Prodigy, 9.1 for the Demetech Calscan, and 8.5 for the Osteometer Dexacare G4. To learn more, you could read Dr. Wrights excellent book about it explains absolutely everything you need to know about BHRT. So, yes, I would take more vitamin K2. Since you are taking AlgaeCal Plus and thus getting at least twice as much calcium as strontium, you are never going to absorb more strontium than calcium. Thank you so much, you give an unbelievable amount of time freely to help people who cannot get this kind of help from their doctor. I hope you will give AlgaeCal a try when you need to reorder you calcium supps. hi lara idont knowif my email will reach you what does the website refers to? In Your Bones, Ive laid out how you can figure out what you are getting from your diet and then what the supplement options are, so you can better determine what you need. Also those on vitamin D and vitamin K2, both of which are essential for ensuring proper absorption and utilization of calcium and magnesium. I just started taking AlgaeCal Plus and Strontium Citrate. Would you have access to a means of contacting Li through the HKU Scholars Hub? Any help would be greatly appreciated! Should be taking 340 mg/d of strontium Boost for the next ~50 years strontium and 69 % citrate was what. Be sure to have higher BMD and also greater risk of breast cancer.! 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